Papers
Showing 164 published or preprint papers authored by the Bennett Institute.
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Educational interventions delivered to prescribing advisers to influence primary care prescribing: a very low-cost pragmatic randomised trial using routine data from OpenPrescribing.net
A low cost randomised trial of an educational intervention in CCGs to influence prescribing of low-priority items
Status: Preprint
Categories
- OpenPrescribing
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Ursodeoxycholic acid and severe COVID-19 outcomes in people with liver disease
Cohort study investigating whether ursodeoxycholic acid was associated with COVID-19 related hospitalisation and death in people with primary biliary cirrhosis and primary sclerosing cholangitis.
Status: Preprint
Categories
- OpenSAFELY
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Impact of COVID-19 on mental illness in vaccinated and unvaccinated people
This study examined associations of COVID-19 with subsequent mental illness in the pre-vaccination period of the pandemic and for unvaccinated and vaccinated people after vaccination became available.
Status: Preprint
Categories
- OpenSAFELY
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Implementing Germ Defence digital behaviour change intervention via all primary care practices in England to reduce respiratory infections during the COVID-19 pandemic
Germ Defence is an evidence-based interactive website that promotes behaviour change for infection control within households. To maximise the potential of Germ Defence to effectively reduce the spread of COVID-19, the intervention needed to be implemented at scale rapidly.
Status: Published
Categories
- OpenSAFELY
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Clinical and health inequality risk factors for non-COVID-related sepsis during the global COVID-19 pandemic
We used OpenSAFELY-TPP data to elucidate the association between non-Covid-19 related sepsis and a range of risk factors during the Covid-19 pandemic
Status: Published
Categories
- OpenSAFELY
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Interpreting pathology test result values with comparators (<, >) in Electronic Health Records research
A short data report about comparators in pathology test results
Status: Published
Categories
- OpenSAFELY
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Antibiotics for Common Infections in Primary Care Before, During and after the COVID-19 Pandemic and Extent of Risk-Based Prescribing: Need for Personalised Guidelines
We assessed the changes in risk-based prescribing behaviours of antibiotics for common infections in primary care during the Covid-19 pandemic.
Status: Published
Categories
- OpenSAFELY
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The impact of the COVID-19 pandemic on the treatment of common infections in primary care and the change to antibiotic prescribing in England
We studied how antibiotic precribing for common infections in primary changed duding the Covid-19 pandemic and how this may have affected clincial outcomes
Status: Published
Categories
- OpenSAFELY
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Impact of the COVID-19 pandemic on antipsychotic prescribing in individuals with autism, dementia, learning disability, serious mental illness or living in a care home
We describe the impact of the the COVID-19 pandemic on antipsychotic prescribing in those with autism, dementia, learning disability, serious mental illness or living in a care home.
Status: Published
Categories
- OpenSAFELY
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Challenges in Estimating the Effectiveness of 2 Doses of COVID-19 Vaccine Beyond 6 Months in England
This paper discusses the challenges in estimating long-term (>6 months) vaccine effectiveness in observational data, primarily due to high uptake of a subsequent third vaccine dose.
Status: Published
Categories
- OpenSAFELY
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Gout incidence and management during the COVID-19 pandemic in England, UK
Assessing how the COVID-19 pandemic impacted incidence and quality of care for people with gout in England, UK.
Status: Published
Categories
- OpenSAFELY
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Healthcare in England was affected by the COVID-19 pandemic across the pancreatic cancer pathway
The pandemic affected healthcare in England across the pancreatic cancer pathway. Positive lessons could be learnt from the services that were resilient and those that recovered quickly
Status: Published
Categories
- OpenSAFELY
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Living alone and mental health: parallel analyses in UK longitudinal population surveys and electronic health records prior to and during the COVID-19 pandemic
People living alone have poorer mental health and lower life satisfaction. During the pandemic, this gap in self-reported distress remained; however, there was a narrowing of the gap in service use.
Status: Published
Categories
- OpenSAFELY
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Eleven key measures for monitoring general practice clinical activity during COVID-19
This paper presents an important effort to develop an open-source software framework for monitoring trends and variations in healthcare over time in England. They demonstrate a compelling example of how this system can track key healthcare indicators over the course of the COVID-19 pandemic.
Status: Published
Categories
- OpenSAFELY
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Evaluation of the impact of COVID-19 pandemic on hospital admission related to common infections
We studied the changes in hospital admission rates for common infections during the Covid-19 pandemic, for those having and having not received antibiotic prescriptions in primary care
Status: Published
Categories
- OpenSAFELY
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Repeated antibiotic exposure and risk of hospitalisation and death following COVID-19 infection
We examined whether prior frequent antibiotic exposure is associated with severe COVID-19 outcomes.
Status: Published
Categories
- OpenSAFELY
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Ethnic differences in the indirect effects of the COVID-19 pandemic on clinical monitoring and hospitalisations for non-COVID conditions in England
We aimed to describe the impact of pandemic-related disruption on ethnic differences in clinical monitoring and hospital admissions for non-COVID conditions in England.
Status: Published
Categories
- OpenSAFELY
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Patient Characteristics Associated with Repeat Antibiotic Prescribing Pre- and during the COVID-19 Pandemic
With the approval of NHS England, we conducted a retrospective cohort study of >19 million English primary care patient records using the OpenSAFELY-TPP analytics platform. We analysed repeat/non-repeat prescribing frequency in monthly patient cohorts between January 2020 and 2022.
Status: Published
Categories
- OpenSAFELY